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Their medical staff can help you set up another time to receive your Injectafer dose. In severe cases, it can cause asthma-like symptoms, such as wheezing and difficulty breathing. In this group, after 35 days of treatment: In clinical studies, Injectafer was effective in treating IDA in adults with CKD who didnt require dialysis. The drug helps increase your hemoglobin level back to a value thats within the normal range. Its caused by your body not having enough iron, which is needed to make hemoglobin. If you have any questions about Venofer, please talk with your doctor, nurse, pharmacist, or other health care provider. (A generic drug is an exact copy of the active drug in a brand-name medication.) If you miss an appointment for your Injectafer dose, youll need to call your doctors office. Injectafer comes as a liquid solution inside vials. 1 0 obj Side effectswill last a very long time if the cause of them is not resolved. Venofer is indicated to treat iron deficiency anemia (IDA) in adult and pediatric patients (2 years and older) with chronic kidney disease (CKD). This could happen because Injectafer helps increase their hemoglobin levels, but it doesnt address the underlying cause of their anemia. This gives a total cumulative dose of 1,500 mg of Injectafer. Use Venofer as ordered by your doctor. (Hemoglobin is a protein thats found in your red blood cells.). Together, you and your doctor can discuss the benefits and risks of treatment options for anemia. This survey is being conducted by the WebMD marketing sciences department. (See also Notes section.). Side effects from HRT depend on a number of factors: taste impairment. Weight influences how fast medication breaks down in the body, so it also affects how longside effectswill last. You may report side effects to Health Canada at 1-866-234-2345. People with IDA have low blood levels of hemoglobin. reactions at the site of the injection. wAd**CgI%"nn{Oa[q{r5 Infusions should be administered over at least 15 minutes. We comply with the HONcode standard for trustworthy health information. If youre not sure if youll need to get prior authorization for Injectafer, contact your insurance company. Discuss the risks and benefits with your doctor. If youre taking iron pills, be sure to tell your doctor before starting Injectafer. Cholesterolmedication may reduce the risk of a stroke but it can decrease the quality of life for some people but causingweight gain, dizziness, nausea, and musclepain. But its not known whether this poses any risk to a child whos breastfed. The actual price youll pay depends on your insurance plan and any copays, your location, and the pharmacy you use. Your doctor will go over your Severeside effectscan lead to injury or death -drowsinesscan cause a car accident or injury when operating heavymachinery. Review our medical disclaimer. Other drugs are available that can treat iron deficiency anemia (IDA). Low iron saturation, or iron deficiency, has various possible causes. All patients receiving Venofer require periodic blood tests to monitor the amount of iron in the blood. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. Can diet help improve depression symptoms? *Patients are calculated based on an estimated annual cumulative dose. Depending on your doctors instructions and Call your doctor right away if you have chest pain, cough or the need to cough, dizziness, passing out, shortness of breath, sweating, or throat tightness. IQVIA [NSP Audit from MAT November 2013 to November 2018]. Reactions around the injection/infusion site, such as pain, irritation, itching, bleeding, or discoloration after leakage of injection into the skin. The body cannot metabolize such a high dose fast enough, so it ends up affecting a part of the body it wasnt intended to, such as the stomach. Symptoms include shock, dangerously low blood pressure, loss of consciousness, and/or collapse. reese0809 1 yr. ago. Side effects are uncomfortable reactions to medications or drugs. Call your healthcare provider or get medical help right away if you have symptoms of an allergic reaction, including but not limited to rash, chest pain, cough, dizziness, passing out, shortness of breath, sweating or throat tightness. Suffering from somemedical conditionsput people at risk fordrugside effectsof medications for other health concerns. The rest of the people switched from taking iron by mouth to taking an iron product other than Injectafer thats given by IV. In the first group, some people continued taking iron by mouth, while other people took Injectafer. Patients with iron-deficiency anemia who are having high blood loss surgery (> 500 ml) within the next 2 months and need to replace iron quickly. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. You will be watched closely for at least 30 minutes to make sure you do not have an allergic reaction. Its not known how often people taking a treatment other than Injectafer had diarrhea. Treatment with Venofer injections can make it harder for your body to absorb iron medications you take by mouth. Venofer Side Effects. It may also cause nervousness, restlessness, and difficulty sleeping in some people. Heart failure: Could a low sodium diet sometimes do more harm than good? Notify your healthcare provider of any irritation at the injection site. This is why the FDA hasa programcalledMedWatchthat encourages Americans to report adversereactions. It belongs to a class of medications known as iron replacement products. Terminal half-life ranges from 7 to 12 hours. This is not a complete list of side effects and others may occur. }|54U|O~?|_v;f\o^(W+/-|^)O65_)rd sm }[x[)y.z Wz?9_jV0ub,`g`s?oXOSp/Kgw$b!Vb$;IvBVR9n|\0ln=;/=,mgw@do,[";/8nJL{n}Bb-|^6[~>a_1H'^M:^vv=iM+x|+Y No, Injectafer itself wont make you gain weight. How long it takes for the bodyto break down the meds matters and some peoples bodies simply take longer than others. In pediatric patients the most common side effects (>2%) are headache, viral respiratory tract infection, peritonitis, upset stomach, throwing up, fever, dizziness, cough, arteriovenous fistula thrombosis, hypotension and hypertension (increased blood pressure). Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. Best food forward: Are algae the future of sustainable nutrition? Joint pain. Possibleside effectsareweight gainand suicidal thoughts. (A class of medications describes a group of drugs that work in the same way.). fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes discharge or excessive tearing Clinical trials showed that Injectafer is effective in increasing hemoglobin levels in people with iron deficiency anemia (IDA). In clinical trials,. 5 0 obj Iron is an essential nutrient needed to maintain energy levels and keep you healthy. Dr. Brandon ColbyMDis a US physician specializingin the personalized prevention of disease through the use of genomic technologies. You would receive 15 mg of Injectafer per kilogram of body weight for each of your two doses. Use of the term female in this article refers to sex assigned at birth. Mental healthdisorders like depression may requireantidepressantsto treat. They can tell you about other medications that may work well for you. Grapefruitjuice may be healthy for people to drink, but it can cause someseriousside effects. In clinical studies, people who took Injectafer still had iron in their system that was released by the drug 24 days after theyd gotten their injection. But you dont necessarily need to eat these foods unless your doctor tells you to do so. Can poor sleep impact your weight loss goals? MNT is the registered trade mark of Healthline Media. Diarrhea is a common side effect of most iron replacement products, which is the group of drugs that Injectafer belongs to. For some people, it may be OK to continue taking a multivitamin that contains iron. If you have questions about side effects, call your doctor. Also tell them about any vitamins, herbs, and supplements you use. Back pain. Otherwise, call a poison control center right away. One class of immune checkpoint inhibitors targets the protein PD-1, which acts as a brake to keep the immune system in check. After receiving IV iron therapy, you will be monitored for 30 minutes to make sure you do not have an allergic reaction or a drop in blood pressure. . Injectafer isnt known to interact with any other medications, herbs, supplements, or foods. If this happens, you may need to get another treatment course of Injectafer, if your doctor recommends it for you. endobj Call your doctor for medical advice about side effects. This is because alcohol reduces your bodys absorption of certain nutrients that are necessary to make red blood cells. An LSD comedown is when the mental and hallucinatory effects have worn . You should always consult your doctor or another healthcare professional before taking any medication. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. How is Venofer (iron sucrose) given? Keep in mind that there may be additional costs related to getting your doses of the drug at a medical facility. Canada residents can call a provincial poison control center. Have blood work checked as you have been told by the doctor. Medically reviewed by Sanjai Sinha, MD. When the toxins are released into the air, they can be inhaled and cause irritation to the lungs. . There have also been reports of serious allergic reactions to Venofer. Some may be a better fit for you than others. Below are examples of these side effects. You are encouraged to report side effects to American Regent, Inc. at 1-800-734-9236 or to the FDA by visiting www.fda.gov/medwatch or calling 1-800-FDA-1088. However, many people have no side effects or only have minor side effects. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Injectafer is indicated to treat iron deficiency anemia (IDA) in adults who meet one of the following criteria: Injectafer is administered intravenously, either by intravenous (IV) infusion or as an undiluted, slow IV push. After getting each dose of Injectafer, your healthcare professional will monitor you for at least 30 minutes. The researchers found that compared with their hemoglobin level before the study: But the actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. You will be watched closely by your doctor for 30 minutes after each dose. The oral form of the drug, called sucroferric oxyhydroxide and used . Change in taste. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Limited data indicate that breastmilk iron is not increased after intravenous infusion of Venofer. The Injectafer dosage your doctor prescribes will depend on your body weight. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. They have been a god send. muscle pain. This hormone is made by your kidneys. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. For instance, there are some experts who believe there are long-lastingside effectsfromCOVIDthat were not aware of just yet. monitor along with your hemoglobin and red blood cell count: The Venofer patient brochure provides information and support for CKD patients (2 years and older) with IDA. If you think there has been an overdose, call your poison control center or get medical care right away. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Nose or throat irritation. Most mild side effects of Injectafer typically go away within about 30 minutes of receiving your dose of the drug. Iron sucrose can harm an unborn baby if you have a severe reaction to this medicine during your second or third trimester. In the study, peoples hemoglobin level was measured to check for improvement in their anemia. If you need financial support to pay for Injectafer, or if you need help understanding your insurance coverage, help is available. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. <> Daiichi Sankyo, Inc., the manufacturer of Injectafer, offers a program called injectconnect, which may help lower the cost of the drug. Side effects: DayQuil can cause side effects such as drowsiness, dizziness, nausea, vomiting, and stomach upset. As with most drugs, some people can have an allergic reaction after taking Injectafer. The Food and Drug Administration (FDA) approves prescription drugs such as Injectafer to treat certain conditions. ByDr. If you have questions about the safety of breastfeeding while youre taking Injectafer, talk with your doctor. This includes people who: Usually, hypophosphatemia doesnt cause symptoms. Since side effects are similar between 150 mg and 300 mg, a larger dose may increase severity or frequency of side effects. Keep out of reach of children. In this group, after 35 days of treatment: Effectiveness of Injectafer compared with a different IV iron product. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. For more information about Injectafers approved uses, see the section Injectafer uses below. Last updated on Feb 20, 2023. Venofer (iron sucrose injection, USP) is indicated for the treatment of iron deficiency anemia (IDA) in adult and pediatric (2 years of age and older) patients with chronic kidney disease (CKD), and is administered only by or under the supervision of your healthcare provider. Theyll do this by checking certain blood tests. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. Injectafer isnt a medication that youll take regularly on a schedule. With IV infusion, the drug is given as a slow drip into your vein over a period of time. Venofer is given as an infusion into a vein. Always review your medical history with the treatingphysician. Total cumulative Venofer dose = number of 100mg ampoules for Hb increase. Do not flush down a toilet or pour down a drain unless you are told to do so. Taking a higher dose than needed can often lead to adverse effects. Before you receive Venofer, tell your doctor if you have low blood pressure, hepatitis, or if you have received many blood transfusions in the past. We cancelled my 5th because of the reaction. The recommended dosing guidelines of Injectafer for treating IDA are based on patient weight, as follows: Injectafer contains ferric carboxymaltose, which is a polymer that releases iron into the body. However, not treating iron deficiency anemia during pregnancy may cause complications such as premature birth or low birth weight. Tell all of your health care providers that you take Venofer. As described just above in the Allergic reaction section, some people may have an allergic reaction after getting a dose of Injectafer. After the infusion, you can drive yourself home and return to your usual activities. You may also need to monitor your blood pressure at home. Injectafer and Feraheme have different approved uses, but theyre both used to treat IDA in certain adults. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. 3 0 obj People who weigh less than 110 lb (about 50 kg) will receive two separate Injectafer doses of 15 mg/kg of body weight. If administering via IV infusion, up to 750 mg of Injectafer should be diluted in no more than 250 mL of sterile 0.9% sodium chloride solution (NaCl). To help make sure that you dont miss appointments for your Injectafer doses, try setting an appointment reminder on your phone. With a delayed reaction, your body reacts to a drug that youve been exposed to in the past without having a reaction. Do not use Injectafer in people with a history of hypersensitivity reactions to Injectafer or any components of the drug product. However, there has been a report of delayed allergic reaction in someone receiving a second dose of Injectafer. For reasons we dont fully understand, some peoples immune system gets over-activated when the drug enters their body. upper respiratory infection. Why is the range so wide? But for other people, their IDA returns after treatment with Injectafer. Orofer S 100 Injection 1 Injection in 1 Packet 286 301 5% off. Ask your doctor or healthcare provider if Venofer is the right choice for you. The following lists contain some of the key side effects that may occur while taking Injectafer. Injectafer can be exposed to temperatures between 59F to 86F (15C to 30F) for a short period of time. Only 10 mg may be excreted by the body the next time it goes through the liver, and possibly only 5 mg the nextpass. Both of theseside effectscould worsen depression and lead tolife-threateningconsequences. You may need extra iron because of blood loss during kidney dialysis. Potential injection site discoloration has happened. Injectafer and Venofer are both brand-name drugs. Diarrhea. Patients should induce vomiting or evacuate the stomach by lavage during Venofer overdoasge. Call your doctor right away if you have serious side effects. The next time the doctor prescribesprescription medication, ask aboutcommonside effectsand if they are known to last a short or longtime. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. Evenbirth controlcan lead to severeside effectslike bloodclots. Should I avoid certain foods while taking Venofer Vial? Venofer (iron sucrose) injection, USP is an intravenous (IV) form of iron, which is a key ingredient for making new red blood cells. This is why family members often have the same issues with drugs as others in theirfamily. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. In clinical studies, Injectafer was effective in treating IDA in adults who either didnt improve with or had side effects from taking iron by mouth. Venofer also comes as a liquid thats given by either IV infusion or a slow IV injection. Together, you and your doctor can develop a treatment plan thats best for you. Is the ketogenic diet right for autoimmune conditions? These changes could help improve your anemia on a long-term basis. I had my first infusion of 1gm 10 days ago. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. This medicine may cause serious types . A variety of tests can diagnose iron deficiency anemia. Follow your doctor's directions carefully. Tell your doctor if you are taking iron supplements or other iron-based oral medications. Heres some detail on certain side effects this drug may cause. Consult your pharmacist or local waste disposal company. This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. %PDF-1.3 Innovators Monograph Which tests can diagnose iron deficiency anemia? If you have questions about the best diet for you during Injectafer treatment, talk with your doctor. Fortunately, knowing how longside effectslast can help those suffering know what to donext. It is given into a vein for a period of time. Your body then uses the iron from Injectafer to make hemoglobin and new RBCs. However, some people can experienceside effectsfor much longer - days, months, or indefinitely. There are 2 tests that your doctor will likely As a result, you may not make as much EPO as usual. For example, some people with anemia have extreme fatigue (lack of energy), which can make it hard for them to exercise. In one study, treatment with Injectafer was compared with that of iron thats taken by mouth. The dosing for iron replacement treatment in pediatric patients less than 2 years old with Peritoneal or Hemodialysis-Dependent CKD or Non-Dialysis-Dependent CKD have not been established.